#1
cause of cancer death lung cancer
20%
lower mortality with annual LDCT screening
0.90
model accuracy (AUPRC) predicting non-adherence
4
number of languages supported
Research Overview
Where you live can be as strong a predictor of whether you'll get screened for lung cancer as your own health history. This study set out to understand why; and to build a way to close that gap before it costs someone an early diagnosis.
Current Situation
Racial/ethnic minorities and lower-income patients face higher lung cancer risk but historically lower screening adherence. This study looks at individual and neighborhood-level factors to find out why.
Our Approach
A two-phase model: build and validate a predictive tool, then use it in real time to connect high-risk patients with support. See timeline below.
Main Goals of the Study
Complete
Phase 1 (Cohort C)
Use the model in real-time to predict which patients are at high-risk for non-adherence and administer patient navigator intervention to those at high-risk.
In Progress
Phase 2 (Cohort C)
Use the model in real-time to predict which patients are at high-risk for non-adherence and administer patient navigator intervention to those at high-risk.
"Because of this program, one participant's lung cancer was caught at
Stage I; when it's most treatable."
Individual factors
- Demographics and background
- Tobacco use
- Social needs
- Experiences of discrimination
- LC risk perception, LCS, and health status
Neighbourhood factors
- Residential segregation
- Neighborhood deprivation
- Transportation
- Walkability
- Poverty levels
Are You Eligibility?
This study was built for communities like yours; here's how to tell if you're one of them.
You speak English, Spanish, Armenian, or Mandarin
You identify as African American, Asian, Latinx/Hispanic, Native American, or mixed/more than one race
You meet USPSTF lung cancer screening guidelines at the time of your baseline LDCT
You receive care at a partner site (City of Hope, ParkTree Community Healthcare Center)
You completed a baseline LDCT scan within the last 3 months
How to Participate
1
Check eligibility
Talk to your care team or use the checklist above.
2
Consent & survey
Complete a short consent form and baseline survey.
3
Get your risk result
Our model estimates your screening risk.
4
Navigation support
High-risk participants get navigator check-ins.
5
15-month check-in
We confirm your record and ask for feedback.
Participate now
Frequently Asked Questions
What languages is this study available in?
This study is currently available in English, Spanish, Armenian, and Mandarin. Translation support and materials are provided by our study team.
What happens if I'm found to be high-risk?
If you are found to be high-risk, a dedicated patient navigator will contact you directly to discuss the results, guide you through the next steps, and coordinate care.
Will participating affect my care at City of Hope?
No, participating in this study will not affect your standard clinical care at City of Hope. It is designed to complement and enhance your health monitoring.
How is my data used and protected?
Your privacy is our top priority. All personal and health data is strictly de-identified, encrypted, and stored securely in compliance with HIPAA guidelines.
Who do I contact with questions?
For any questions, you can contact the primary study team at contact@hace-lje-research.org or speak directly with your attending physician.